Cyproheptadine is a histamine drug that has antagonist properties and is used in the treatment of allergic runny nose, inflammation due to allergy, and many other symptoms. This drug is also known to be a first-generation antihistamine also having anesthetic properties when applied locally. Cyproheptadine is also a widely prescribed drug and is used mostly by children and is a part of common available first-aid boxes, and is an over-the-counter medication.
Histamines are naturally occurring chemicals within the body, which when provoked causes classical allergy symptoms like small wheals or bumps on the skin, eye irritation, runny nose, itching, and a wide range of symptoms.
Antihistamines are synthetic or man-made compounds that act upon histamines and prevent their action. There are many types of antihistamines that vary in their degree of action and efficacy, and Cyproheptadine is one of the foremost compounds that has been isolated initially and is still being used.
One important thing of using drugs that have been initially been discovered is the fact that sufficient data are available, and a better insight is available into their mode of action and how they really work.
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Available Dosage Forms
The most common available dosage form is the tablet form.
Cyproheptadine 4 mg tablets ( Adult)
Cyproheptadine 2 mg tablet (Child/Pediatric)
Cyproheptadine Suspension
How To Use Cyproheptadine
Cyproheptadine tablet is to be taken with lukewarm water as directed by the physician, and can be taken 2 to 3 times a day, as continuous presence of the drug in the body is essential for better result.
Cyproheptadine suspension is to be carefully measured in a teaspoon or a measuring cup that would be available with the suspension bottle itself.
In case of difficulty taking the pill in its solid form, the pill could be crushed using a pill crusher and then taken in the powder form, but this could be avoided if possible.
In children, the drug is usually 2 mg, and is prescribed according to the age, height, and weight of the child, the child’s present medical condition, and other drugs the child is on.
The drug could be taken with or without food, as drug taken after food will help better absorption of the drug. Medical advice and physician instruction is of foremost importance in cases of dose adjustments in patients taking this drug for substantial period of time. The drug is to be stored in a clean cool place away from children.
Clinical Indications and Prescription Information
- Allergic Conditions.
- Asthma exacerbation.
- Allergic response to asthma.
- Drug-induced parkinsonism.
- Itching of eye, nose, and hives.
- Loss of appetite in children.
Contraindications, who should not take this drug.
The drug is contraindicated to persons suffering from:
- Open angle and narrow angle glaucoma.
- High blood pressure that is longstanding.
- Kidney disease or kidney injury.
- Diabetes.
- Liver diseases.
- Enlarged prostate, as histamines are found in larger concentration in the prostate.
- Children below 1 month of age.
- Pregnant and nursing women.
In-Depth Information On Cyproheptadine and Histamine.
Histamines are naturally-occurring substances in the body, and when released cause allergic symptoms like runny nose, watery eyes, itching, burning sensation, and hives. These histamines are released into the bloodstream when body mistakes harmless substances to be a foreign body and triggers an “Alert Response” to the body, (something like when the firealarm goes on when you show torchlight on the sensors).
Cyproheptadine being an antihistamine exerts its action against the histamines, binds to them and prevents them from exerting the action. As long as the drug is present in the blood stream and binds with the histamines, they could no longer function. This is the reason why continuous presence of the drug is essential for suppression of symptoms and to bring the body back to its normal self.